ABSTRACT
Confluent and reticulate papillomatosis is a rare but clinically distinct dermatosis first described by Gougerot and Carteaud in 1927. It consists of dark brown pigmented papules which coalesce to reticulate and confluent patches. It usually begins shortly after puberty mainly in females and is most often localized to the intermammary and interscapular regions. Histological examination shows hyperkeratosis and papillomatosis, and there may be decreased granular cell layer, focal acanthosis, or hypermelanosis of the basal cell layer. We recently observed a 20-year-old male patient who showed typical clinical and histopathological findings of confluent and reticuIate papillomatosis. Treatment with an aromatic analog of vitamin A acid(Ro 10-9359) resulted in dramatic effectivenese.
Subject(s)
Adolescent , Female , Humans , Male , Young Adult , Hyperpigmentation , Papilloma , Puberty , Skin Diseases , Tretinoin , Vitamin A , VitaminsABSTRACT
Verrucous hemangioma is a variant of a capillary, cavernous, or mixed hemangioma which undergoes a reactive proliferative epidermal change. Most verrucous hemangiomas appear on the lower extremities, and most are present at birth or appear during childhood. We observed two patients who showed typical clinical and histopathological findings of verrucous hemangioma. Treatment was done by wide surgical excision and skin graft. The first rnale patient had a good therapeutic result but the second female patient had a recurrence at one month post-operative.
Subject(s)
Female , Humans , Capillaries , Hemangioma , Lower Extremity , Parturition , Recurrence , Skin , TransplantsABSTRACT
Juvenile Hyalin Fibromatosis is a rare congenital disease that is characterized by large tumors, especially on the scalp, small whitish nodules, hypertrophy of the gingiva, and flexural contractures of the large joints of the limbs. A review of the world literature disclosed 13 similar cases, under various names. This case is the 14th case in the literature and the first case in Korea. A 3 year old girl had multiple large tumors and nodules on various parts of the bodis, hypertrophic gingiva, and flexural contracture of the elbow and knee joints. The histopathologic features of the tumor were characteristic of Juvenile Hyalin Fibromatosis. The tumor cells were embedded in an amorphous eosinophilic ground substance. Diagnosis was confirmed by clinical features and histopathological findings.
Subject(s)
Child, Preschool , Female , Humans , Contracture , Diagnosis , Elbow , Eosinophils , Extremities , Fibroma , Gingiva , Hyalin , Hypertrophy , Joints , Knee Joint , Korea , ScalpABSTRACT
Lidex' cream (Fluocinonide 0.05% in FAPG base) is a new fluorina,ted topical corticosteroid, and its clinical effect was assessed by applying topically three to four times daily to the lesions of 50 patients with a variety of inflamrnatory skin condi- tions. The results revealed excellent effect in 16 patients, moderate effect in 23 patients, slight improvement in 9 patients, and no effect in 2 patients. No unfavorable side effects were noted except blanching. The findings suggest that fluocinonide is an excelIent addition to the topical corticosteroid agents that are available for clinical use at the present time.